Electra Swimsuit Card:
Enter THEHAND as a code.

All Fantastic 4 Comics:
Enter SavageLand as a code.

Unknown Effect:
Enter MONROE as a code.

Unknown Effect:
Enter Reiko as a code.

Unknown Effect:
Enter NZONE as a code.

Play as Brigade:
Successfully complete the Iron Man 3 mission in story mode.

Play as Daredevil:
Successfully complete the Daredevil 3 mission in story mode.

Play as Fault Zone:
Successfully complete the Storm 3 mission in story mode.

Play as Hazmat:
Successfully complete the Magneto 3 mission in story mode.

Play as Iron Man:
Successfully complete the Iron Man 3 mission in story mode.

Play as Magneto:
Successfully complete the Magneto 3 mission in story mode.

Play as Paragon:
Successfully complete the Paragon 3 mission in story mode.

Play as Solara:
Successfully complete the Venom 3 mission in story mode.

Play as Storm:
Successfully complete the Storm 3 mission in story mode.

Play as Van Roekel:
Successfully complete the Paragon 4 mission in story mode.

Play as Venom:
Successfully complete the Venom 3 mission in story mode.

Daily Bugle Rooftop arena:
In versus mode, fight as Spider-Man vs. Venom (CPU) in the NYC bridge arena. Win to unlock the Daily Bugle Rooftop arena. Note: You may need to complete the game first.